Primary Immunodeficiency occurs when the immune system works poorly and does not work correctly. The immune system, which forms the defense mechanism against diseases and keeps microbes under control, constitutes an immunodeficiency state if it is insufficient. So what is Primary Immunodeficiency? Questions about the symptoms and treatment of Primary Immunodeficiency.

iHealth member and Istanbul hospital Internal Medicine Specialist Doctor, she gave important information about Primary Immunodeficiency affecting children and adults.

What is Primary Immunodeficiency?

Doctor, it is a set of diseases that are accompanied by chronic or recurrent infections that develop due to hereditary or congenital causes. Primary immunodeficiency, which is very common, especially in children born from inbreeding, is much less common in developed countries. The little-known, and therefore difficult-to-diagnose disease occurs when the immune system works poorly and does not work correctly, and represents more than 300 diseases.

What are the symptoms of Primary Immunodeficiency?

– Recurrent infections

– Recurrent ear and sinusitis infections

– Growth retardation

– Growth of lymph nodes and spleen

– Diarrhea accompanied by weight loss

– Recurrent abscesses of tissues or organs

– Thrush or fungal infections.

How is Primary Immunodeficiency treated?

If the genetic factors are the cause of PI, which is easy to pass on hereditarily, the treatment approaches related to solving this problem are followed first. At this point, preventive measures are taken with screening tests in Turkey.

In addition, a significant distance has been traveled in the field of PIY thanks to transplantation procedures such as bone marrow, stem cells and thymus.


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President of Organ Transplant Center at MedicalPark Hospital Antalya

Turkey's world-renowned organ transplant specialist. Dr. Demirbaş has 104 international publications and 102 national publications.

Physician's Resume:

Born on August 7, 1963 in Çorum, Prof. Dr. Alper Demirbaş has been continuing his work as the President of MedicalPark Antalya Hospital Organ Transplantation Center since 2008.

Prof. who performed the first tissue incompatible kidney transplant in Turkey, the first blood type incompatible kidney transplant, the first kidney-pancreas transplant program and the first cadaveric donor and live donor liver transplant in Antalya. Dr. As of August 2016, Alper Demirbaş has performed 4900 kidney transplants, 500 liver transplants and 95 pancreas transplants.

In addition to being the chairman of 6 national congresses, he has also been an invited speaker at 12 international and 65 national scientific congresses. Dr. Alper Demirbaş was married and the father of 1 girl and 1 boy.


Eczacibasi Medical Award of 2002, Akdeniz University Service Award of 2005, Izder Medical Man of the Year Award of 2006, BÖHAK Medical Man of the Year Award of 2007, Sabah Mediterranean Newspaper Scientist of the Year Award of 2007, ANTIKAD Scientist of the Year Award of 2009, Social Ethics Association Award of 2010, Işık University Medical Man of the Year Award of 2015, VTV Antalya's Brand Value Award of 2015.


Doctor of Medicine Degree Hacettepe University Faculty of Medicine Ankara, General Surgeon Ministry of Health Turkey EKFMG (0-477-343-8), University of Miami School of Medicine Member of Multiple Organ Transplant, ASTS Multiorgan Transplant Scholarship. Lecturer at Kyoto University. Lecturer at University of Essen, Research assistant at the University of Cambridge .

Professional Members:

American Society of Transplant Surgeons, American Transplantation Society Nominated, Middle East and Southern Africa Council Transplantation Society 2007, International Liver Transplantation Association, Turkish Transplantation Association, Turkish Society of Surgery, Turkish Hepatobiliary Surgery Association.


Our website contents consist of articles approved by our Web and Medical Editorial Board with the contributions of our physicians. Our contents are prepared only for informational purposes for public benefit. Be sure to consult your doctor for diagnosis and treatment.
Medically Reviewed by Professor Doctor Alper Demirbaş
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