Stem cells are the first cells that begin to form after fertilization in the human mother’s womb. It is considered one of the biggest developments in the field of medicine in recent years. Bone marrow, stem cells; cells that produce bone marrow and blood cells are called. Blood cells are made up of cells that provide oxygen to tissues or protect the body from microbes and defend against bleeding. If the bone marrow does not work, there is a decrease in blood cells and the patient’s life is put at risk. The transferred cells, regardless of which region of the body they are located, are tranformed in a short time by keeping up with the characteristics of that region. When applied to damaged organs, it can help to complete that area and return to its former state in a short time. Stem cells are very special cell types that have a unique feature such as the ability to regenerate themselves and produce autonomous cells.

Most of the stem cells were obtained from unused egg samples taken from expectant parents who want to have in vitro fertilization. Stem and progenitor (progenitor) cells in adults are involved in the healing and repair of the body and have the ability to regenerate adult tissues. Currently, stem cells that can show a high amount of variability are widely used in medical treatments such as bone marrow transplants. Stem cell transplantation is one of the methods used in the treatment of some blood diseases and bone marrow insufficiencies, as well as congenital blood diseases.Stem cells have the ability to produce all the cells found in the bone marrow and blood.

Although stem cell transplantation received the name bone marrow transplantation in the early years only because it was taken from the bone marrow, hematopoietic (blood-forming) stem cell transplantation is used more often today, since transplants are performed using stem cells circulating in the blood more often.

In order for a cell to become a stem cell, it must have the following two properties:

Self-renewal: The ability to perform a large number of cell divisions by continuing its undifferentiated phase.

Competence: The ability to differentiate into specialized cell types. Stem cells need to have multipotent or unipotent characteristics that give them the ability to change into any mature cell type. Separately from this; it is also said that stem cell function is regulated by a form of feedback.

The accessible adult stem cell sources are 3, these are;

Bone marrow; it is necessary to take it from the femur or pelvis by biopsy and to purify the cells.

Fat (adipose) tissue (fat cells) ; they should be taken with liposuction and purified.

Blood is provided by purification with the help of a “pheresis”, in which the blood passes through and stem cells are filtered, similar to a blood donation from a donor to a recipient.

Stem cells can also be obtained from umbilical cord blood at the end of pregnancy, that is, immediately after childbirth. Of all stem cell types, self-acquisition has the least risk and they can be stored in banks and used for later. But recent studies also indicate that the use of autologous stem cells in cancer treatments may be risky. For this purpose, they must be artificially grown in cell culture media and modified according to the cell type to be used in these environments.



Follow me
President of Organ Transplant Center at MedicalPark Hospital Antalya

Turkey's world-renowned organ transplant specialist. Dr. Demirbaş has 104 international publications and 102 national publications.

Physician's Resume:

Born on August 7, 1963 in Çorum, Prof. Dr. Alper Demirbaş has been continuing his work as the President of MedicalPark Antalya Hospital Organ Transplantation Center since 2008.

Prof. who performed the first tissue incompatible kidney transplant in Turkey, the first blood type incompatible kidney transplant, the first kidney-pancreas transplant program and the first cadaveric donor and live donor liver transplant in Antalya. Dr. As of August 2016, Alper Demirbaş has performed 4900 kidney transplants, 500 liver transplants and 95 pancreas transplants.

In addition to being the chairman of 6 national congresses, he has also been an invited speaker at 12 international and 65 national scientific congresses. Dr. Alper Demirbaş was married and the father of 1 girl and 1 boy.


Eczacibasi Medical Award of 2002, Akdeniz University Service Award of 2005, Izder Medical Man of the Year Award of 2006, BÖHAK Medical Man of the Year Award of 2007, Sabah Mediterranean Newspaper Scientist of the Year Award of 2007, ANTIKAD Scientist of the Year Award of 2009, Social Ethics Association Award of 2010, Işık University Medical Man of the Year Award of 2015, VTV Antalya's Brand Value Award of 2015.


Doctor of Medicine Degree Hacettepe University Faculty of Medicine Ankara, General Surgeon Ministry of Health Turkey EKFMG (0-477-343-8), University of Miami School of Medicine Member of Multiple Organ Transplant, ASTS Multiorgan Transplant Scholarship. Lecturer at Kyoto University. Lecturer at University of Essen, Research assistant at the University of Cambridge .

Professional Members:

American Society of Transplant Surgeons, American Transplantation Society Nominated, Middle East and Southern Africa Council Transplantation Society 2007, International Liver Transplantation Association, Turkish Transplantation Association, Turkish Society of Surgery, Turkish Hepatobiliary Surgery Association.


Our website contents consist of articles approved by our Web and Medical Editorial Board with the contributions of our physicians. Our contents are prepared only for informational purposes for public benefit. Be sure to consult your doctor for diagnosis and treatment.
Medically Reviewed by Professor Doctor Alper Demirbaş
Follow me