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People’s endocrine system is sensitive to many items and substances that we use in our daily life. Even the World Health Organization, many medical institutions and institutes report that we may be exposed to these chemicals in furniture, kitchenware, food packaging, cosmetic products or workplaces. The negative effects of these substances that block the endocrine system on our health have been reported in many scientific studies. Cognitive impairments, developmental disorders, obesity, diabetes, endometriosis, fibroids, infertility, birth defects, premature births, miscarriages, cardiovascular diseases, thyroid problems, female genital cancers, prostate problems have been shown to be associated with many health problems such as.

It is unlikely that the effects of these chemicals can be explained only by the amount of the dose exposed. An unfortunate timing, the moment of interaction with another chemical, genetic predisposition or the presence of many other different factors cause these chemicals to be effective even at low doses.


1- Atrazine (ATR)

Banned in the European Union in 2004. It is found in pesticide and herbicide contaminated soils. It passes through the endocrine, respiratory and nervous systems. Creates liver damage.

2- Bisphenols (BPA)

Their use was restricted in 2012. It is found in polycarbonate plastics, epoxy resins, plastic toys, bottles and food packaging. It has estrogenic, fattening, thyroid gland and reproductive system effects.

3- Dichlorodiphenyldichloroethylene (DDT)

Banned in 1972. It is transmitted from contaminated water, grain, fish. The half-life in the body is 6-10 years. It is carcinogenic, affects the nervous system, kidneys, liver and peripheral nervous system.

4- Di (2-ethylhexyl) Phthalate

Restricted between 1971 and 1975. It is taken by injection and vaginal suppositories. It is a carcinogen, teratogen that crosses the placenta.

5- 17-estradiol (EE2)

It is found in birth control pills and contaminated water. There are no restrictions and prohibitions. It is believed that they cause cardiovascular, brain vascular, thromboembolic and gallbladder diseases and have carcinogenic effects.

6- Methoxychlor (MXC)

Banned in the USA as a pesticide in 2003. It is found in contaminated soil, water and food. It suppresses the central nervous system, causes liver and kidney damage, has developmental and reproductive side effects in animals, hereditary kidney and ovarian diseases, and has a fattening effect.

7- Polychlorinated biphenyls (PCBs)

Banned in 1979. It is transmitted by contaminated air and food, skin contact and old electrical appliances. The half-life in the body varies between 12 days and 16 years. Carcinogenic, destructive to the stomach and liver, reproductive, nervous system and thyroid gland effects are found.

8- Phthalates (Phtl)

Restricted in 2009. It is found in foodstuffs, PVC plastics and floor coverings, personal care products, medical supplies and piping systems. Carcinogenic, damaging to the liver, has developmental and developmental effects on the reproductive system, asthma-causing and fattening effects.

9- Perfluorooctanoic acid (PFOA)

Voluntary production was restricted in the USA in 2015. Contaminated food and water are found in dust, floor polishes, fire tube dust, electrical cables, food packaging and non-contaminated carpets. It has liver effects, effects on mammary gland development, immune system toxic and carcinogenic effects.

10- 2, 3, 7, 8-tetrachlorodibenzop-dioxin (TCDD)

It’s production is not restricted. It is found in the by-product of the herbicide, casting material, chlorinated weighing paper. The half-life in the body is 7-11 years. It has damage-causing, weight-losing, thymus gland-reducing, immune-suppressing, reproductive system-affecting and carcinogenic effects on the liver.

11- Vinklozolin (Vncl)

It’s production is not restricted. It is found in the food and business environment. It has antiandrogenic, effects on male reproduction and the nervous system, constructive and possible carcinogenic effects of genetically transmitted reproductive diseases.

Some measures should be taken at the social level to prevent exposure to chemicals that block the endocrine system. First of all, the public needs to be educated. It should be ensured that chemicals that block the endocrine system are kept away from water, air and soil. They should also be kept away, especially from developing children.

Chemicals that interfere with the endocrine system are not easily measured in routine. For this reason, economic kits that will allow easy measurement in society should be developed and made available to society.

Turkey Medicals Co-ordinator, “It should be ensured that a generation of scientists sensitive and sensitive to this issue is raised in the academic and health sector, and that candidates for the health sector who are growing up become aware of this issue.” was said.



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President of Organ Transplant Center at MedicalPark Hospital Antalya

Turkey's world-renowned organ transplant specialist. Dr. Demirbaş has 104 international publications and 102 national publications.

Physician's Resume:

Born on August 7, 1963 in Çorum, Prof. Dr. Alper Demirbaş has been continuing his work as the President of MedicalPark Antalya Hospital Organ Transplantation Center since 2008.

Prof. who performed the first tissue incompatible kidney transplant in Turkey, the first blood type incompatible kidney transplant, the first kidney-pancreas transplant program and the first cadaveric donor and live donor liver transplant in Antalya. Dr. As of August 2016, Alper Demirbaş has performed 4900 kidney transplants, 500 liver transplants and 95 pancreas transplants.

In addition to being the chairman of 6 national congresses, he has also been an invited speaker at 12 international and 65 national scientific congresses. Dr. Alper Demirbaş was married and the father of 1 girl and 1 boy.


Eczacibasi Medical Award of 2002, Akdeniz University Service Award of 2005, Izder Medical Man of the Year Award of 2006, BÖHAK Medical Man of the Year Award of 2007, Sabah Mediterranean Newspaper Scientist of the Year Award of 2007, ANTIKAD Scientist of the Year Award of 2009, Social Ethics Association Award of 2010, Işık University Medical Man of the Year Award of 2015, VTV Antalya's Brand Value Award of 2015.


Doctor of Medicine Degree Hacettepe University Faculty of Medicine Ankara, General Surgeon Ministry of Health Turkey EKFMG (0-477-343-8), University of Miami School of Medicine Member of Multiple Organ Transplant, ASTS Multiorgan Transplant Scholarship. Lecturer at Kyoto University. Lecturer at University of Essen, Research assistant at the University of Cambridge .

Professional Members:

American Society of Transplant Surgeons, American Transplantation Society Nominated, Middle East and Southern Africa Council Transplantation Society 2007, International Liver Transplantation Association, Turkish Transplantation Association, Turkish Society of Surgery, Turkish Hepatobiliary Surgery Association.


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Medically Reviewed by Professor Doctor Alper Demirbaş
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