A liver biopsy is important in the evaluation of liver diseases. However, today, thanks to new technologies, it is now possible to measure the liver with ultrasound waves instead of a biopsy, said Prof. Dr. “Measurements can be made in minutes with fibroscan, which is an easily applied procedure in liver examinations. The liver sampling area is growing 100 times and a wider area is being evaluated with the fibroscan device, which is an alternative method to liver biopsy for determining chronic liver diseases. There are also no side effects,”he explained.

A gastroenterologist who emphasizes that a liver biopsy is very important for accurately determining the stages of liver disease, making a treatment decision for chronic liver diseases, and then monitoring treatment, Prof. Dr. “The method called ‘transient elastography’ performed with the Fibroscan device comes across as an important application in the evaluation of liver fibrosis with both its non-interventional and its reproducibility,” said.

The elasticity of tissues is measured numerically

Turkey Medicals member and Mersin hospital Gastroenterologist Prof. Dr. Who said that Fibroscan is a device that numerically measures the elasticity of soft tissues using the transient elastography method. Dr. “Fibroscan sends low frequency ultrasonic vibrations to the liver tissue and the resulting wave propagates by multiplying in the tissue. The speed of transmission of the wave here is associated with the elasticity of the tissue through which it passes. Therefore, as the hardness of the tissue increases, the propagation speed of the wave also increases. Here the device detects this speed and creates a numerical result and objectively reveals the amount of fibrosis in the liver,” he said.

There is no need to remove parts from the liver

Stating that the Fibroscan process does not require the removal of parts from the liver according to the biopsy, Gastroenterologist Prof. Dr. “In this process, the liver as a whole is evaluated in a much broader way. This is a very important advantage over a biopsy. It is very important that it is especially easy to apply, performed in minutes, and no pain or pain is felt. In addition, it is a side-ineffective method, since it is not an interventional procedure. Moreover, no special preparation is needed before it, except for going hungry. The fact that it is repeatable is also one of its important advantages. Thanks to this method, the level of liver lubrication and the level of damage can be determined by measuring the flexibility, hardness of the liver,” he said.

Diseases in which the method is used

Stating that Fibroscan technology can be used in all liver diseases that cause chronic liver damage, Gastroenterologist Prof. Dr. explained the diseases in which the method is used as follows:

Liver enzyme Heights, viral disease, hepatitis, hepatitis C, Hepatitis D (delta hepatitis), autoimmune hepatitis, drug-induced chronic liver damage, primary biliary cholangitis (bile ducts of autoimmune disease), preoperative risk assessment for liver cirrhosis linked to non-portal hypertension, Wilson’s disease, in which regardless of the reason, due to accumulation of fatty liver damage and infection (hepatosteatoz fat).


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President of Organ Transplant Center at MedicalPark Hospital Antalya

Turkey's world-renowned organ transplant specialist. Dr. Demirbaş has 104 international publications and 102 national publications.

Physician's Resume:

Born on August 7, 1963 in Çorum, Prof. Dr. Alper Demirbaş has been continuing his work as the President of MedicalPark Antalya Hospital Organ Transplantation Center since 2008.

Prof. who performed the first tissue incompatible kidney transplant in Turkey, the first blood type incompatible kidney transplant, the first kidney-pancreas transplant program and the first cadaveric donor and live donor liver transplant in Antalya. Dr. As of August 2016, Alper Demirbaş has performed 4900 kidney transplants, 500 liver transplants and 95 pancreas transplants.

In addition to being the chairman of 6 national congresses, he has also been an invited speaker at 12 international and 65 national scientific congresses. Dr. Alper Demirbaş was married and the father of 1 girl and 1 boy.


Eczacibasi Medical Award of 2002, Akdeniz University Service Award of 2005, Izder Medical Man of the Year Award of 2006, BÖHAK Medical Man of the Year Award of 2007, Sabah Mediterranean Newspaper Scientist of the Year Award of 2007, ANTIKAD Scientist of the Year Award of 2009, Social Ethics Association Award of 2010, Işık University Medical Man of the Year Award of 2015, VTV Antalya's Brand Value Award of 2015.


Doctor of Medicine Degree Hacettepe University Faculty of Medicine Ankara, General Surgeon Ministry of Health Turkey EKFMG (0-477-343-8), University of Miami School of Medicine Member of Multiple Organ Transplant, ASTS Multiorgan Transplant Scholarship. Lecturer at Kyoto University. Lecturer at University of Essen, Research assistant at the University of Cambridge .

Professional Members:

American Society of Transplant Surgeons, American Transplantation Society Nominated, Middle East and Southern Africa Council Transplantation Society 2007, International Liver Transplantation Association, Turkish Transplantation Association, Turkish Society of Surgery, Turkish Hepatobiliary Surgery Association.


Our website contents consist of articles approved by our Web and Medical Editorial Board with the contributions of our physicians. Our contents are prepared only for informational purposes for public benefit. Be sure to consult your doctor for diagnosis and treatment.
Medically Reviewed by Professor Doctor Alper Demirbaş
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