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BREAKTHROUGH BRAIN TUMOR DIAGNOSIS: COULD BE DETECTED BY URINE TEST
Japanese scientists have discovered that brain cancer, which is difficult to diagnose early, can be detected by a urine test. The developed test is seen as a groundbreaking discovery to prevent disease progression and death rates.
Brain cancer is seen as a difficult type to diagnose early, as patients are usually only given a CT or MRI scan after developing neurological symptoms. In general, the process progresses as doctors recommend screening to analyze the structure of the brain after symptoms, and diagnose abnormal tissue after these scans. But when diagnosed, it may have been too late for the surgery to completely eliminate the growth.
According to a study published in Applied Materials & Interfaces, Nagoya University researchers have prepared a microRNA urine test that could significantly speed up the diagnosis of brain cancer and save lives.
MicroRNAs are small nucleic acid molecules released by different cells in body fluids such as blood and urine. The researchers focused on these tiny particles and developed a process to find molecules that could act as early warning signs for brain tumors.
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ONE HUNDRED PERCENT SENSITIVITY, 97 PERCENT DIAGNOSIS
“Urine can easily be collected without putting a burden on the human body, “Atsushi Natsume, an associate professor at Nagoya University, said in a statement. Urine-based fluid biopsies for patients with brain tumors have not been fully investigated because none of the traditional methodologies can efficiently remove microRNAs from the urine in terms of variety and quantity. So we decided to develop a device that could do that,” he said.
The research team explained that many microRNA from brain tumors are found in a stable state in the urine. They used their device to analyze samples taken from brain cancer patients and their controls. The study says the device can diagnose brain tumors with 100 percent sensitivity and 97 percent specificity, regardless of the size and malignancy of the tumors. That means the study correctly identified 100 percent of cancer patients and 97 percent of non-cancer volunteers.
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IT COULD BE DIAGNOSED ONE DAY IN THE FUTURE
Nagoya University scientists believe the new test could be used to diagnose various types of brain cancer early. Associate professor Atsushi Natsume stressed that in the future, with a combination of artificial intelligence and telemedicine, people can know the existence of cancer, and doctors can also diagnose the condition of cancer patients only with a small amount of their daily urine.
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Turkey's world-renowned organ transplant specialist. Dr. Demirbaş has 104 international publications and 102 national publications.
Physician's Resume:
Born on August 7, 1963 in Çorum, Prof. Dr. Alper Demirbaş has been continuing his work as the President of MedicalPark Antalya Hospital Organ Transplantation Center since 2008.
Prof. who performed the first tissue incompatible kidney transplant in Turkey, the first blood type incompatible kidney transplant, the first kidney-pancreas transplant program and the first cadaveric donor and live donor liver transplant in Antalya. Dr. As of August 2016, Alper Demirbaş has performed 4900 kidney transplants, 500 liver transplants and 95 pancreas transplants.
In addition to being the chairman of 6 national congresses, he has also been an invited speaker at 12 international and 65 national scientific congresses. Dr. Alper Demirbaş was married and the father of 1 girl and 1 boy.
Awards:
Eczacibasi Medical Award of 2002, Akdeniz University Service Award of 2005, Izder Medical Man of the Year Award of 2006, BÖHAK Medical Man of the Year Award of 2007, Sabah Mediterranean Newspaper Scientist of the Year Award of 2007, ANTIKAD Scientist of the Year Award of 2009, Social Ethics Association Award of 2010, Işık University Medical Man of the Year Award of 2015, VTV Antalya's Brand Value Award of 2015.
Certificates:
Doctor of Medicine Degree Hacettepe University Faculty of Medicine Ankara, General Surgeon Ministry of Health Turkey EKFMG (0-477-343-8), University of Miami School of Medicine Member of Multiple Organ Transplant, ASTS Multiorgan Transplant Scholarship. Lecturer at Kyoto University. Lecturer at University of Essen, Research assistant at the University of Cambridge .
Professional Members:
American Society of Transplant Surgeons, American Transplantation Society Nominated, Middle East and Southern Africa Council Transplantation Society 2007, International Liver Transplantation Association, Turkish Transplantation Association, Turkish Society of Surgery, Turkish Hepatobiliary Surgery Association.
Disclaimer:
Our website contents consist of articles approved by our Web and Medical Editorial Board with the contributions of our physicians. Our contents are prepared only for informational purposes for public benefit. Be sure to consult your doctor for diagnosis and treatment.