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BEWARE OF ABDOMINAL PAIN THAT LASTS FOR TWO DAYS! DISEASE CAN BE FMF
Abdominal pain can be ‘Familial Mediterranean Fever’ (FMF), experts say, this disease most often occurs between the ages of 5 and 15.
Symptoms of FMF disease, known as familial Mediterranean fever, are being investigated by citizens. FMF is noted as a rheumatic disease with a genetic transition that is accompanied by recurrent episodes of abdominal pain and fever. In the disease, which most often occurs between the ages of 5 and 15, 90 percent of cases can also be diagnosed at an older age, even if they are diagnosed before the age of 20. Here are some things to know about Mediterranean fever.
Turkey iHealth member Rheumatology Specialist Doctor, referring to the symptoms of the disease and how to make a diagnosis, gave the following information:
The most important symptom of the disease is abdominal pain and fever attacks, which usually last for 2-3 days. Attacks the decurrent at irregular intervals and can last from a week to several months between two attacks. Between attacks, the person is completely normal and has no complaints. In some patients, chest pain, pain and swelling in the joints, red rashes on the legs, vomiting-diarrhea, pain and tenderness in the scrotum (erbezes) may occur during attacks.
There are no special tests for the diagnosis of FMF. After excluding other possible diseases, a diagnosis can be made by a doctor depending on whether there are signs or not. These diagnoses; The presence of FMF clinical symptoms (unexplained fever, severe abdominal, chest or joint pain), family history (mother, father, brothers, sisters and relatives increases your risk of having FMF), blood tests (during attacks white blood cells, erythrocyte sedimentation rate, CRP and an increase in fibrinogen levels was found, although none are not specific to the disease), the diagnosis of FMF and FMF supports positive response to colchicine drugs called genetic tests can support the diagnosis by showing mutations that can cause disease.
It can be confused with other diseases
Explaining why diagnosis is delayed and who has the disease, Dr. described the symptoms that distinguish Mediterranean fever from other diseases as follows:
It is difficult to diagnose FMF initially because the symptoms that occur during attacks are not specific to the disease. This disease is often confused with appendicitis due to abdominal pain and fever. Some patients may even have appendicitis surgery. It can be confused with other rheumatic diseases due to pain and swelling in the joints. There are no specific laboratory signs of the disease. The high sedimentation rate, increased CRP and fibrinogen levels observed during attacks are common signs of all inflammatory diseases and are not distinguishable.
Genetic tests can help diagnose, especially in patients with atypical signs. The disease is genetically transmitted from mother and father to children. Mom or dad may have FMF. However, this is not essential. Although mom and dad look completely healthy, their children may have FMF if there is a genetic carrier. Again, the risk of developing FMF is also high in those who have FMF disease in close relatives.
How is Mediterranean fever treated?
Speaking about the treatment process of the disease, Dr. said:
Genetic diseases such as FMF, 11 of pregnancy. it can be detected by DNA analysis obtained from fetal samples taken from the week of. However, FMF is distinguished from other genetic diseases by being a treatable disease. For this reason, prenatal diagnosis for FMF is not applied today because there is no need to terminate the pregnancy. There is no treatment method that completely eliminates FMF disease from the body. The most effective drug used is colchicine. This drug is effective as long as it is used. In those who have stopped taking the drug, the disease begins again. Therefore, the treatment of colchicine should be continued for life.
In those who do not continue treatment regularly, the kidneys are damaged due to amyloidosis over the years. The patient goes into renal failure and may have to continue living as a dialysis patient. Patients should be monitored regularly for the development of kidney damage. The only way to protect yourself from kidney failure is to use colchicine for life. In patients whose complaints cannot be controlled with colchicine, biological agents are used. All of these drugs are drugs that are used in combination with colchicine in the form of injections, that is, needles.
Stress and excessive physical fatigue can increase frequency of attacks. Therefore, stress and excessive fatigue should be avoided. The relationship of the disease with diet and nutrition has not been shown. There is no herbal product whose effectiveness and reliability in the treatment of this disease have been medically demonstrated. Colchicine, which we use for treatment, can disrupt liver function. Herbal products that will be used with colchicine can further adversely affect liver function. Before using such herbal support products, a Turkish doctor at hospital should definitely be consulted.