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For the first time the concept of telomeres was introduced by Hermann J. In 1938. It has been described by Muller. The question of what is a telomere is also being investigated. So what is a telomere? What does a telomere do? Here are the details about the topic.

For the first time the concept of telomere was introduced by Hermann J. In 1938. Muller identified Drosophila by studying the melanogaster chromosome. Muller studied the structure changes after X-radiation and the incidence of these changes. As a result of his studies, he found that deletions and inversions in the end regions of chromosomes are very rare.

As research has progressed, it has been observed that broken-ended chromosomes merge more easily, and the telomere structures of normal chromosomes are stable, neither the ends of broken-ended chromosomes nor the ends of other telomeres do not merge. After this information, it was assumed that there are special terminal structures that ensure the integrity of the chromosomes. So what is a telomere, what does it do? Here are the details…

What is a telomere?

Telomeres are DNA structures located at the two ends of chromosomes. The telomere, located at the end of the DNA helices located in all cells in the body, protects the chromosomes.

Telomeres also shorten every time cells divide to keep the body healthy and young. In addition, factors such as smoking, stress, sedentary life, and improper eating patterns also cause telomeres to shorten.

What does a telomere do?

Telomeres with resistance to exonucleases and ligases are known to be involved in chromosome stability, nuclear structuring, gene expression, completion of replication of chromosome ends and preventing these ends from mixing with each other or reacting with the inner parts of chromosomes, tumor formation, aging and cell division.


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President of Organ Transplant Center at MedicalPark Hospital Antalya

Turkey's world-renowned organ transplant specialist. Dr. Demirbaş has 104 international publications and 102 national publications.

Physician's Resume:

Born on August 7, 1963 in Çorum, Prof. Dr. Alper Demirbaş has been continuing his work as the President of MedicalPark Antalya Hospital Organ Transplantation Center since 2008.

Prof. who performed the first tissue incompatible kidney transplant in Turkey, the first blood type incompatible kidney transplant, the first kidney-pancreas transplant program and the first cadaveric donor and live donor liver transplant in Antalya. Dr. As of August 2016, Alper Demirbaş has performed 4900 kidney transplants, 500 liver transplants and 95 pancreas transplants.

In addition to being the chairman of 6 national congresses, he has also been an invited speaker at 12 international and 65 national scientific congresses. Dr. Alper Demirbaş was married and the father of 1 girl and 1 boy.


Eczacibasi Medical Award of 2002, Akdeniz University Service Award of 2005, Izder Medical Man of the Year Award of 2006, BÖHAK Medical Man of the Year Award of 2007, Sabah Mediterranean Newspaper Scientist of the Year Award of 2007, ANTIKAD Scientist of the Year Award of 2009, Social Ethics Association Award of 2010, Işık University Medical Man of the Year Award of 2015, VTV Antalya's Brand Value Award of 2015.


Doctor of Medicine Degree Hacettepe University Faculty of Medicine Ankara, General Surgeon Ministry of Health Turkey EKFMG (0-477-343-8), University of Miami School of Medicine Member of Multiple Organ Transplant, ASTS Multiorgan Transplant Scholarship. Lecturer at Kyoto University. Lecturer at University of Essen, Research assistant at the University of Cambridge .

Professional Members:

American Society of Transplant Surgeons, American Transplantation Society Nominated, Middle East and Southern Africa Council Transplantation Society 2007, International Liver Transplantation Association, Turkish Transplantation Association, Turkish Society of Surgery, Turkish Hepatobiliary Surgery Association.


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Medically Reviewed by Professor Doctor Alper Demirbaş
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