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WHAT IS A TELOMERE, WHAT DOES IT DO? INFORMATION ABOUT THE TELOMERE
For the first time the concept of telomeres was introduced by Hermann J. In 1938. It has been described by Muller. The question of what is a telomere is also being investigated. So what is a telomere? What does a telomere do? Here are the details about the topic.
For the first time the concept of telomere was introduced by Hermann J. In 1938. Muller identified Drosophila by studying the melanogaster chromosome. Muller studied the structure changes after X-radiation and the incidence of these changes. As a result of his studies, he found that deletions and inversions in the end regions of chromosomes are very rare.
As research has progressed, it has been observed that broken-ended chromosomes merge more easily, and the telomere structures of normal chromosomes are stable, neither the ends of broken-ended chromosomes nor the ends of other telomeres do not merge. After this information, it was assumed that there are special terminal structures that ensure the integrity of the chromosomes. So what is a telomere, what does it do? Here are the details…
What is a telomere?
Telomeres are DNA structures located at the two ends of chromosomes. The telomere, located at the end of the DNA helices located in all cells in the body, protects the chromosomes.
Telomeres also shorten every time cells divide to keep the body healthy and young. In addition, factors such as smoking, stress, sedentary life, and improper eating patterns also cause telomeres to shorten.
What does a telomere do?
Telomeres with resistance to exonucleases and ligases are known to be involved in chromosome stability, nuclear structuring, gene expression, completion of replication of chromosome ends and preventing these ends from mixing with each other or reacting with the inner parts of chromosomes, tumor formation, aging and cell division.
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