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The biggest reason for the loosening, sagging and lines that occur on the skin depending on age is that the body reduces its own natural collagen production over the years. For this reason, it is necessary to prefer processes that support collagen production in medical aesthetic procedures. Stating that it is important that the procedures performed create the desired fullness on the skin and contribute to the production of collagen from the skin, Turkey Medicals member Turkish Medical Aesthetic Physician Dr. he gave information about the ‘Smart Fill’ application, which provides these two functions at the same time.

“Increasing collagen production is one of the most important points in skin rejuvenation applications. During the aging process, there is a deterioration and damage to the structure of collagen contained in our skin. The quality of collagen decreases, and the equivalent of this condition on the skin is relaxation and loss of elasticity. In addition, skin collagen is also reduced in quantity due to the fact that the breakdown is excessive and not enough new ones can be produced instead.

As a result, with the participation of gravity in the process, the fullness on the cheekbones decreases, discharge and sagging on the cheeks, deepening in the groove of the edge of the nose, the appearance of laughing lines, the formation of cigarette lines on the lip, shrinkage of the lip and sagging on the edge of the mouth occur.

Smart filler is very successful in increasing collagen

In recent years, the desire to delay the signs of aging has become quite important for both women and men. Due to this growing demand, the development of many medical aesthetic methods and applications that fight aging has been in question. In this process, it is aimed to increase the amount of collagen and the quality of collagen produced by stimulating the body’s own collagen production mechanisms. A smart filler that has recently been very preferred, which produces our own collagen, is very successful in eliminating all the problems I mentioned related to age.

What is included in the content of the smart filler?

The smart filler consists of polycarbonate.In studies conducted after the injection of this particular substance, electron microscope images have shown the production and increase of type 1 collagen, which is very important for the skin. As a result, when the PCL particles are fully bioabsorbed,a sufficient amount of collagen is formed that will give the lifting effect and fullness.

Caprolactone, which has been used safely as a sewing thread in surgical applications for about 30 years, stimulates collagen-producing cells, leading to the production of new and strong collagen of the tissue. With its biocompatible structure, the incidence of allergy side effects is almost negligible when applied with the right techniques.

How to apply smart filler?

Collagen stimulating fillers are very easy to apply as with other fillers. Therefore, it can be expressed as a small touch. It is painless due to its administration with a local anesthetic. After the application, daily life can be returned immediately.

The slight fullness that appears at the time of the first application belongs to the gel and disappears in a few weeks. It is necessary to wait for the expiration of 3-4 months for the real effect. Because this time is needed for sufficient collagen formation. At the end of this period, the desired lifting effect and fullness of the skin are observed, as well as an improvement in skin quality and appearance.

The smart filler can provide persistence for up to 4 years

The smart filler is available in four separate forms, which can provide durability from one to four years. It can be applied anywhere with volume and lifting requirements, except for lips and eyes in the face area.

It is applied to improve skin quality and elasticity in the back of the hands, neck and décolleté. It can also help with scars on the face, deep acne scars.

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President of Organ Transplant Center at MedicalPark Hospital Antalya

Turkey's world-renowned organ transplant specialist. Dr. Demirbaş has 104 international publications and 102 national publications.

Physician's Resume:

Born on August 7, 1963 in Çorum, Prof. Dr. Alper Demirbaş has been continuing his work as the President of MedicalPark Antalya Hospital Organ Transplantation Center since 2008.

Prof. who performed the first tissue incompatible kidney transplant in Turkey, the first blood type incompatible kidney transplant, the first kidney-pancreas transplant program and the first cadaveric donor and live donor liver transplant in Antalya. Dr. As of August 2016, Alper Demirbaş has performed 4900 kidney transplants, 500 liver transplants and 95 pancreas transplants.

In addition to being the chairman of 6 national congresses, he has also been an invited speaker at 12 international and 65 national scientific congresses. Dr. Alper Demirbaş was married and the father of 1 girl and 1 boy.


Eczacibasi Medical Award of 2002, Akdeniz University Service Award of 2005, Izder Medical Man of the Year Award of 2006, BÖHAK Medical Man of the Year Award of 2007, Sabah Mediterranean Newspaper Scientist of the Year Award of 2007, ANTIKAD Scientist of the Year Award of 2009, Social Ethics Association Award of 2010, Işık University Medical Man of the Year Award of 2015, VTV Antalya's Brand Value Award of 2015.


Doctor of Medicine Degree Hacettepe University Faculty of Medicine Ankara, General Surgeon Ministry of Health Turkey EKFMG (0-477-343-8), University of Miami School of Medicine Member of Multiple Organ Transplant, ASTS Multiorgan Transplant Scholarship. Lecturer at Kyoto University. Lecturer at University of Essen, Research assistant at the University of Cambridge .

Professional Members:

American Society of Transplant Surgeons, American Transplantation Society Nominated, Middle East and Southern Africa Council Transplantation Society 2007, International Liver Transplantation Association, Turkish Transplantation Association, Turkish Society of Surgery, Turkish Hepatobiliary Surgery Association.


Our website contents consist of articles approved by our Web and Medical Editorial Board with the contributions of our physicians. Our contents are prepared only for informational purposes for public benefit. Be sure to consult your doctor for diagnosis and treatment.
Medically Reviewed by Professor Doctor Alper Demirbaş
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