One of the most common reasons for contacting orthopedic outpatient clinics is knee pain. The most common cause of these pains, especially in those over the age of 50, is knee calcification. Turkey Medicals member and JCI hospital department Orthopedics and Traumatology Specialist Doctor “PRP injections applied to the knee help maintain knee function in patients with early-stage knee calcification,” said about the injection treatment…

Recalling that knee calcification can be defined as a weakening and deterioration of the structure of the knee cartilage, which allows the knee joints to move, for various reasons, Orthopedics and Traumatology Specialist Dr. “This deterioration can lead to a decrease in the patency of the knee joint movement over time and a decrease in the quality of life, making it difficult for a person to walk,” said. Addressing the importance of using the human body’s self-healing potential in parallel with advances in technology, that is, developments in regenerative treatment approaches, Doctor “PRP (Platelet-Rich Plasma), which is also successfully used, especially for the early treatment of knee calcification, is one of the most popular applications of the innovative point of view,” was said.


Underlining that PRP, that is, platelet-rich plasma, is a form of biological therapy derived from a person’s own blood, Turkish Orthopedics and Traumatology Specialist Dr. “Platelet-rich plasma therapy is a method aimed at harnessing the body’s self-healing abilities. The platelets in the main structure of PRP are actually made up of cells that form the clot that stops bleeding that occurs in cases of injury. But these cells also have a structure that includes growth factors that contribute to the repair and healing of tissues. When these growth factors are activated, they can help repair damaged tissues by supporting the body’s own recovery mechanisms. Regenerative treatment approaches also exist to take advantage of this feature of our body,” he said.


Emphasizing that only one tube of blood to be taken from the patient is enough for PRP treatment, Orthopedics and Traumatology Specialist Dr. in Antalya “By separating the cells we call platelets from the blood taken, a plasma liquid rich in platelets is obtained. Normally, an average of 150-400,000 platelets are present in 1 milliliter of blood, while in PRP this rate can reach more than 1 million. Another advantage of PRP is that it can activate local stem cells that are in a quiet state, which makes it a natural drug treatment. The dose and process of treatment may vary depending on the degree of the disease,” the statement said.


He said that knee calcifications have stages 1 to 4 depending on the condition of the disease. Dr. “4 refers to the most severe, and 1 refers to the initial knee calcification disease. In the medical literature, it has been observed that the effect of PRP applications is very good, especially in stage 1 and stage 2 patients, and that it relieves pain in stage 3 patients. In stage 4 patients, the most appropriate option is not PRP, but surgical knee replacement applications,” he said. Reminding that PRP is not applied to those who have a family history of cancer, those who use blood thinners, those who have blood diseases, those who have infections and inflammation in the area where the application will be performed, pregnant women and those who are breastfeeding, Dr. “PRP injection helps to maintain knee function in patients with early-stage knee calcification, while also improving the quality of a person’s life by reducing pain,” concluded his words.


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President of Organ Transplant Center at MedicalPark Hospital Antalya

Turkey's world-renowned organ transplant specialist. Dr. Demirbaş has 104 international publications and 102 national publications.

Physician's Resume:

Born on August 7, 1963 in Çorum, Prof. Dr. Alper Demirbaş has been continuing his work as the President of MedicalPark Antalya Hospital Organ Transplantation Center since 2008.

Prof. who performed the first tissue incompatible kidney transplant in Turkey, the first blood type incompatible kidney transplant, the first kidney-pancreas transplant program and the first cadaveric donor and live donor liver transplant in Antalya. Dr. As of August 2016, Alper Demirbaş has performed 4900 kidney transplants, 500 liver transplants and 95 pancreas transplants.

In addition to being the chairman of 6 national congresses, he has also been an invited speaker at 12 international and 65 national scientific congresses. Dr. Alper Demirbaş was married and the father of 1 girl and 1 boy.


Eczacibasi Medical Award of 2002, Akdeniz University Service Award of 2005, Izder Medical Man of the Year Award of 2006, BÖHAK Medical Man of the Year Award of 2007, Sabah Mediterranean Newspaper Scientist of the Year Award of 2007, ANTIKAD Scientist of the Year Award of 2009, Social Ethics Association Award of 2010, Işık University Medical Man of the Year Award of 2015, VTV Antalya's Brand Value Award of 2015.


Doctor of Medicine Degree Hacettepe University Faculty of Medicine Ankara, General Surgeon Ministry of Health Turkey EKFMG (0-477-343-8), University of Miami School of Medicine Member of Multiple Organ Transplant, ASTS Multiorgan Transplant Scholarship. Lecturer at Kyoto University. Lecturer at University of Essen, Research assistant at the University of Cambridge .

Professional Members:

American Society of Transplant Surgeons, American Transplantation Society Nominated, Middle East and Southern Africa Council Transplantation Society 2007, International Liver Transplantation Association, Turkish Transplantation Association, Turkish Society of Surgery, Turkish Hepatobiliary Surgery Association.


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Medically Reviewed by Professor Doctor Alper Demirbaş
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