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RECOMMENDATIONS THAT CAN CURE RECURRENT IVF FAILURE
For couples who want to have a baby and are hoping and expecting with this application, every IVF attempt that results in a failure is a very sad situation, stating that the IVF, Obstetrics and Gynecology Specialist Op. Dr. “The golden key to success in IVF treatments is to obtain eggs of good number and quality. Not every woman achieves the same performance in treatment every month. In other words, the same person who receives eggs of good number and quality in a certain period of time can produce a small number and low quality eggs in another month when his inappropriate response is low,” he said.
Turkey Medicals member and Antalya hospital clinic department, Diseases and Obstetrics Specialist Op. Dr. he made statements about the causes of IVF failure and ways to treat it.
Op. Who said that preparing for IVF application is both a material event in itself and brings difficulties from a spiritual point of view. Dr. emphasizing that it is necessary not to despair immediately in these failures, he said that the important thing is to use the time well and evaluate it.
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CAUSES OF FAILURE
Expressing that the mechanisms that ensure the formation of pregnancy are too complicated to be explained by a single parameter, Op. Dr. “Couples should be examined from a broad perspective and their reasons for not achieving success should be investigated in detail before starting a new trial,” he said. Op. Dr. she shared the reasons for the IVF failure as follows:
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EMBRYO-INDUCED CAUSES
– The genetic structure of the embryo is problematic
– Non-compliance with the drug protocols applied during egg development
– Insufficient cultural conditions in which the embryo develops
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CAUSES OF UTERINE (UTERINE) ORIGIN
– Causes that affect the lining of the uterus (Endometrium)
– Polyps, fibroids, etc. formations in the uterus that prevent the embryo from holding on
– Adhesions caused by past infections or curettage
– Endometriosis disease (chocolate cysts)
– Accumulation of fluid in the tubes (due to a previous infection or operation)
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CAUSES OF MALE ORIGIN
– Severe structural problems in sperm, fractures in the DNA helix
– Chromosomal problems
– Diseases that show a genetic transition
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WHAT TO DO IN CASE OF UNSUCCESSFUL IVF
Speaking about what needs to be done in the treatment of unsuccessful IVF, Op. Dr. “Since there are a wide range of reasons that can lead to this situation, the couple should be dealt with in a far-reaching way and investigated in that way. First, it should be investigated whether the expectant mother and father have genetic or systemic diseases that may be an obstacle to the formation of pregnancy. Chromosome analyzes, genetic clotting factors, immunological studies should be carried out,”he said.
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DETAILED EVALUATION AND TREATMENT OF THE COUPLE
Op. Dr. “When many cases of recurrent IVF failure are evaluated, we encounter deficiencies in their detailed, systemic analysis. Therefore, a good analysis of the pairs from all sides is essential. It is very important that they are evaluated, especially hormonal and immune. A good response to treatment can be obtained when thyroid problems, prolactin levels, undiagnosed insidious rheumatological problems related to the immune system, and problems related to all other systems are resolved. In addition, systemic coagulation defects should not be overlooked in terms of treatment success as well as complications. It plays an important role in embryo implantation indirectly or directly,” he said.
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DETERMINATION OF THE APPROPRIATE TREATMENT PERIOD
Also noting the appropriate timing of treatment is Op. Dr. “The golden key to success in IVF treatments is to obtain eggs of good number and quality. Not every woman achieves the same performance in treatment every month. In other words, the same person who receives eggs of good number and quality in a certain period of time can produce a small number and low quality eggs in another month with a low inappropriate response. In order to predict these periods, it is necessary to evaluate the history of the case well, analyze it well, examine it in detail, and clarify its condition with some special tests. In addition, not every case responds the same to the same protocol and hormone injections. Dose and treatment details should be organized differently depending on the person,” he said.
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CASE-SPECIFIC PREPARATION AND SUPPORT ARE IMPORTANT
Op. Dr. “In cases such as polycystic ovary syndrome, endometriosis, which we often encounter with infertility in many disease groups, case-specific preparation and support pre-treatments affect success fantastically. In addition, in cases where the ovarian reserve is low, that is, the treatment response is low, some special hormonal, herbal, or again different supports depending on the case’s infrastructure ultimately have great effects and ensure success,” he said.
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RISK FACTORS SHOULD BE FOCUSED ON
IVF Operator Doctor, “With the requirement to be customized in male infertility, in some cases, pre-hormone, supports antioxidant and vitamin supplements in doses according to specific risk factors underlying the problem and sperm in sperm quality and fertilization ability of sperm has an effect on genetic damage saying,” descriptions of ended.
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Turkey's world-renowned organ transplant specialist. Dr. Demirbaş has 104 international publications and 102 national publications.
Physician's Resume:
Born on August 7, 1963 in Çorum, Prof. Dr. Alper Demirbaş has been continuing his work as the President of MedicalPark Antalya Hospital Organ Transplantation Center since 2008.
Prof. who performed the first tissue incompatible kidney transplant in Turkey, the first blood type incompatible kidney transplant, the first kidney-pancreas transplant program and the first cadaveric donor and live donor liver transplant in Antalya. Dr. As of August 2016, Alper Demirbaş has performed 4900 kidney transplants, 500 liver transplants and 95 pancreas transplants.
In addition to being the chairman of 6 national congresses, he has also been an invited speaker at 12 international and 65 national scientific congresses. Dr. Alper Demirbaş was married and the father of 1 girl and 1 boy.
Awards:
Eczacibasi Medical Award of 2002, Akdeniz University Service Award of 2005, Izder Medical Man of the Year Award of 2006, BÖHAK Medical Man of the Year Award of 2007, Sabah Mediterranean Newspaper Scientist of the Year Award of 2007, ANTIKAD Scientist of the Year Award of 2009, Social Ethics Association Award of 2010, Işık University Medical Man of the Year Award of 2015, VTV Antalya's Brand Value Award of 2015.
Certificates:
Doctor of Medicine Degree Hacettepe University Faculty of Medicine Ankara, General Surgeon Ministry of Health Turkey EKFMG (0-477-343-8), University of Miami School of Medicine Member of Multiple Organ Transplant, ASTS Multiorgan Transplant Scholarship. Lecturer at Kyoto University. Lecturer at University of Essen, Research assistant at the University of Cambridge .
Professional Members:
American Society of Transplant Surgeons, American Transplantation Society Nominated, Middle East and Southern Africa Council Transplantation Society 2007, International Liver Transplantation Association, Turkish Transplantation Association, Turkish Society of Surgery, Turkish Hepatobiliary Surgery Association.
Disclaimer:
Our website contents consist of articles approved by our Web and Medical Editorial Board with the contributions of our physicians. Our contents are prepared only for informational purposes for public benefit. Be sure to consult your doctor for diagnosis and treatment.
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