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GENETIC FACTORS AFFECT 30-50 PERCENT OF CHILDREN’S ALLERGIES
iHealth member and Antalya hospital Specialist in Children’s Health and Diseases Prof. Dr. told about the common allergies in children and their causes. Underlining the importance of allergy tests for children and parents, Prof. Dr. “Genetic factors affect children’s allergies by 30-50 percent,” said.
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Stating that allergy is defined as an abnormal response that occurs after taking substances that are normally harmless to the body by breathing, skin and mouth.
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Prof. Dr. “The reactions caused by the allergen substance taken are the basis of allergic diseases. There are some risk factors that are effective in the occurrence of these diseases. It is known that skin exposure is an important risk factor for this exposure, especially in atopic patients. It is stated that oral intake increases the development of immunotolerance, while skin exposure increases allergy. Violation of the integrity of the skin barrier violation of the integrity of the skin barrier and the transport of the allergen to the lymphatic system through dendritic cells, and then the appearance of an immune response in the body is another reason. Especially in the neonatal period, excessive water loss and increased skin integrity and increased sensitivity to allergens are one of these conditions,”he said.
Prof. Doctor “The most basic element of treatment is to stay away from the allergen. Therefore, the detection of allergen sensitivity is quite important. Frequent attacks of coughing, bloody mucous stools and episodes of diarrhea, treatment received, nose congested, night snoring, coughing after exercise, however, attacks of coughing, weight loss and growth retardation, wheezing, stridor, he has to be rude or sound, common dryness of the skin, redness and itching of the eyes of episodes where the skin is dry, scaly, itchy lesions, inflammation to fluid accumulation in the middle ear and the inner ear, dizziness, blackout, and the sudden swelling of the lip and ear, it should not necessarily be evaluated in terms of episodes of vomiting if you have allergies,” he said.
Allergy is triggered in infants with a decrease in the diversity of intestinal microorganisms, which changes with the use of antibiotics, cigarette exposure, changes in lifestyle and diet, especially in the first trimester of pregnancy, Prof. Dr. “Exposure to vaginal and perianal friendly bacteria during normal delivery prevents allergy. It is known that the frequency of allergies increases even more with increasing cesarean deliveries. With the birth in autumn and winter, the risk of atopic dermatitis and food allergies increases. It is known that the frequency of sudden and life threatening reactions such as anaphylaxis increases with increasing metabolic rate in allergen-sensitive individuals.
Genetic factors are effective by 30-50 percent. Symptoms that indicate an allergy develop by two different mechanisms. Antibodies to allergens play a role in the structure of IgE in such reactions. Signs appear within minutes or hours after contact with the allergen. Allergic rhinitis, asthma, and some food allergies are among these reactions. Decongestant allergic rhinitis is the most common type of allergic rhinitis. These reactions can occur with signs of the skin, oropharyngeal, upper and lower respiratory tract, gastrointestinal tract or cardiovascular system. The reactions are manifested by severe manifestations, ranging from mild manifestations to anaphylaxis. Non-IgE-mediated reactions that develop late: Cellular immunity plays a role in these types of reactions. Symptoms and signs develop after 24-48 hours,” he said.
Along with the tests, parental detection is also important
Prof. Dr. “Along with the tests used to detect allergens, parental detection is also important. But it should also be remembered that there are millions of allergens, such as food dyes, detergents and additives that cannot be tested. There are treatment approaches that should be evaluated on the basis of each allergic disease, such as desensitization studies, oral immunotherapy, non-allergenic foods, adrenaline use,” he said.
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