GENETIC FACTORS AFFECT 30-50 PERCENT OF CHILDREN’S ALLERGIES

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GENETIC FACTORS AFFECT 30-50 PERCENT OF CHILDREN’S ALLERGIES

iHealth member and Antalya hospital Specialist in Children’s Health and Diseases Prof. Dr. told about the common allergies in children and their causes. Underlining the importance of allergy tests for children and parents, Prof. Dr. “Genetic factors affect children’s allergies by 30-50 percent,” said.
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Stating that allergy is defined as an abnormal response that occurs after taking substances that are normally harmless to the body by breathing, skin and mouth.

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Prof. Dr. “The reactions caused by the allergen substance taken are the basis of allergic diseases. There are some risk factors that are effective in the occurrence of these diseases. It is known that skin exposure is an important risk factor for this exposure, especially in atopic patients. It is stated that oral intake increases the development of immunotolerance, while skin exposure increases allergy. Violation of the integrity of the skin barrier violation of the integrity of the skin barrier and the transport of the allergen to the lymphatic system through dendritic cells, and then the appearance of an immune response in the body is another reason. Especially in the neonatal period, excessive water loss and increased skin integrity and increased sensitivity to allergens are one of these conditions,”he said.

Prof. Doctor “The most basic element of treatment is to stay away from the allergen. Therefore, the detection of allergen sensitivity is quite important. Frequent attacks of coughing, bloody mucous stools and episodes of diarrhea, treatment received, nose congested, night snoring, coughing after exercise, however, attacks of coughing, weight loss and growth retardation, wheezing, stridor, he has to be rude or sound, common dryness of the skin, redness and itching of the eyes of episodes where the skin is dry, scaly, itchy lesions, inflammation to fluid accumulation in the middle ear and the inner ear, dizziness, blackout, and the sudden swelling of the lip and ear, it should not necessarily be evaluated in terms of episodes of vomiting if you have allergies,” he said.

Allergy is triggered in infants with a decrease in the diversity of intestinal microorganisms, which changes with the use of antibiotics, cigarette exposure, changes in lifestyle and diet, especially in the first trimester of pregnancy, Prof. Dr. “Exposure to vaginal and perianal friendly bacteria during normal delivery prevents allergy. It is known that the frequency of allergies increases even more with increasing cesarean deliveries. With the birth in autumn and winter, the risk of atopic dermatitis and food allergies increases. It is known that the frequency of sudden and life threatening reactions such as anaphylaxis increases with increasing metabolic rate in allergen-sensitive individuals.

Genetic factors are effective by 30-50 percent. Symptoms that indicate an allergy develop by two different mechanisms. Antibodies to allergens play a role in the structure of IgE in such reactions. Signs appear within minutes or hours after contact with the allergen. Allergic rhinitis, asthma, and some food allergies are among these reactions. Decongestant allergic rhinitis is the most common type of allergic rhinitis. These reactions can occur with signs of the skin, oropharyngeal, upper and lower respiratory tract, gastrointestinal tract or cardiovascular system. The reactions are manifested by severe manifestations, ranging from mild manifestations to anaphylaxis. Non-IgE-mediated reactions that develop late: Cellular immunity plays a role in these types of reactions. Symptoms and signs develop after 24-48 hours,” he said.

Along with the tests, parental detection is also important

Prof. Dr. “Along with the tests used to detect allergens, parental detection is also important. But it should also be remembered that there are millions of allergens, such as food dyes, detergents and additives that cannot be tested. There are treatment approaches that should be evaluated on the basis of each allergic disease, such as desensitization studies, oral immunotherapy, non-allergenic foods, adrenaline use,” he said.

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President of Organ Transplant Center at MedicalPark Hospital Antalya

Turkey's world-renowned organ transplant specialist. Dr. Demirbaş has 104 international publications and 102 national publications.

Physician's Resume:

Born on August 7, 1963 in Çorum, Prof. Dr. Alper Demirbaş has been continuing his work as the President of MedicalPark Antalya Hospital Organ Transplantation Center since 2008.

Prof. who performed the first tissue incompatible kidney transplant in Turkey, the first blood type incompatible kidney transplant, the first kidney-pancreas transplant program and the first cadaveric donor and live donor liver transplant in Antalya. Dr. As of August 2016, Alper Demirbaş has performed 4900 kidney transplants, 500 liver transplants and 95 pancreas transplants.

In addition to being the chairman of 6 national congresses, he has also been an invited speaker at 12 international and 65 national scientific congresses. Dr. Alper Demirbaş was married and the father of 1 girl and 1 boy.

Awards:

Eczacibasi Medical Award of 2002, Akdeniz University Service Award of 2005, Izder Medical Man of the Year Award of 2006, BÖHAK Medical Man of the Year Award of 2007, Sabah Mediterranean Newspaper Scientist of the Year Award of 2007, ANTIKAD Scientist of the Year Award of 2009, Social Ethics Association Award of 2010, Işık University Medical Man of the Year Award of 2015, VTV Antalya's Brand Value Award of 2015.

Certificates:

Doctor of Medicine Degree Hacettepe University Faculty of Medicine Ankara, General Surgeon Ministry of Health Turkey EKFMG (0-477-343-8), University of Miami School of Medicine Member of Multiple Organ Transplant, ASTS Multiorgan Transplant Scholarship. Lecturer at Kyoto University. Lecturer at University of Essen, Research assistant at the University of Cambridge .

Professional Members:

American Society of Transplant Surgeons, American Transplantation Society Nominated, Middle East and Southern Africa Council Transplantation Society 2007, International Liver Transplantation Association, Turkish Transplantation Association, Turkish Society of Surgery, Turkish Hepatobiliary Surgery Association.

Disclaimer:

Our website contents consist of articles approved by our Web and Medical Editorial Board with the contributions of our physicians. Our contents are prepared only for informational purposes for public benefit. Be sure to consult your doctor for diagnosis and treatment.
Medically Reviewed by Professor Doctor Alper Demirbaş
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