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While a person’s kidneys, lungs, liver and heart remain healthy, can his brain age faster than these organs? The answer to that question, unfortunately, is “yes.” “Cognitive reserve theory”, which has been focused on in recent years, is based on the fact that our brain becomes rich or poor as a result of the way we eat from birth, the education we receive, the way we live and the diseases we experience, in other words, “tired early”. So what are the factors that rapidly age our brains?

Turkey Medicals member and Turkish Neuroscientist Doctor Faculty member, explained 6 dangers that cause damage to our brain.

1 – Covid-19 infection

A study conducted at Imperial College London examined the cognitive (cognitive) effects of Kovid-19. In the study, some of these patients identified a kind of ‘mind blur’ in the style of attention, memory and focus disorder, which can persist even months after the signs of Kovid-19 infection have improved. IQ tests showed that patients experienced a loss of up to 10 percent compared to before the Kovid-19 infection.

This table also means that the brains of some of the patients who have had kovid-19 are aged for at least 10 years, and once again reveals the importance of adhering firmly to pandemic measures.

2 – Vascular diseases of the brain

High cholesterol, heart rhythm and valve disorders, high blood pressure (hypertension) and brain-vascular diseases caused by diabetes are among the important diseases decaying the brain. Cholesterol levels that are not well controlled, conditions that affect heart rhythm, and cholesterol levels that can cause atherosclerosis can disrupt the blood supply of the brain, leading to slow or sudden brain damage.

Sudden developing events are usually symptomatic, that is, they give symptoms. But although it can be diagnosed and treated, most patients experience serious permanent damage to brain tissue. Especially small vascular diseases caused by conditions such as diabetes and hypertension that are not under control, if they do not affect critical areas of the brain, for example, areas related to memory, they are mostly silent and insidious.

Millimetric damage as a result of affecting small vessels can merge over many years, causing a large area to be affected and producing some form of dementia or Parkinsonism.

3 – Sleep disorders

Sleep is a process in which the brain rests, empties its garbage and refreshes its strength. Hormones released during sleep are also important for brain and mental health. In addition, abnormal proteins produced in the brain during the day are cleared from the brain during sleep. Sleep disorder causes these abnormal proteins to accumulate, contributing to the pathological process that leads to Alzheimer’s disease. Sleep disorders are therefore serious clinical conditions that not only tire the brain, but can also be directly associated with Alzheimer’s disease.

4 – Eating disorders

A lack of vitamins such as B1, B6, B12 and D, folic acid or important structures such as iron, which are mostly associated with nutritional deficiency, but can also be observed due to impaired absorption as a result of stomach and intestinal diseases, disrupts the function of nerve cells, and if this deficiency lasts for a long time, it can lead to permanent damage to the brain.

But these conditions, which can be diagnosed with very simple screening tests, are among the problems that can be deconstructed most quickly and easily. In addition, in recent years, especially in genetically modified wheat and similar grains is much higher than normal amounts of a protein gluten, which is found in a chronic inflammation mainly in the brain, nutrition, i.e., creating inflammation, headaches, depression, disorders of motivation, and even that can trigger neurodegenerative processes such as Alzheimer’s and Parkinson’s diseases are shown.

5 – Kidney diseases

There are hundreds of chemical reactions in nerve cells every second. Among the most important building blocks of these chemical reactions are electrolytes such as sodium, potassium, chlorine and magnesium.decoction Incomplete or excessive intake of these electrolytes through nutrition, insufficient water drinking, or chronic kidney diseases can lead to electrolyte disorders in the body.

Electrolyte imbalance can cause disorders of consciousness, paralysis-like loss of November strength, and epileptic seizure-like episodes, from forgetfulness, fatigue and drowsiness, to meaningless speech or even a coma.

In addition, in kidney failure, toxic substances that cannot be excreted in the urine can reach the brain through the circulation, causing direct damage. As with other metabolic disorders, this damage can be directly affected by brain function.

As a result of the inability of the kidneys to perform the filtering task, a large increase in the blood level of medications that need to be removed from the kidney can cause side effects in the brain, as if you had taken an overdose of medications. For example, the inability to remove a blood-thinning drug from the kidney and reach an overdose in the blood can lead to bleeding in the brain and other organs. A significant part of kidney disorders observed in old age are seen due to insufficient water drinking.

6 – Inactivity stress

Another important factor that ages the brain prematurely is that most of us suffer from social isolation in the pandemic; ‘inactivity’. It is noted that older people who never left home, remained motionless and experienced intense stress, following the precautions in the Kovid-19 pandemic, although they did not have Kovid-19, their cognitive abilities deteriorated much faster than expected.

This, in turn, shows the negative effects of inactivity and stress on Aging of the brain. In addition, individuals who have experienced chronic depression since their teenage years may have a reduction in the hippocampal areas responsible for memory function in their brains under the influence of stress hormones. This, in turn, can increase the risk of dementia in old age.


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President of Organ Transplant Center at MedicalPark Hospital Antalya

Turkey's world-renowned organ transplant specialist. Dr. Demirbaş has 104 international publications and 102 national publications.

Physician's Resume:

Born on August 7, 1963 in Çorum, Prof. Dr. Alper Demirbaş has been continuing his work as the President of MedicalPark Antalya Hospital Organ Transplantation Center since 2008.

Prof. who performed the first tissue incompatible kidney transplant in Turkey, the first blood type incompatible kidney transplant, the first kidney-pancreas transplant program and the first cadaveric donor and live donor liver transplant in Antalya. Dr. As of August 2016, Alper Demirbaş has performed 4900 kidney transplants, 500 liver transplants and 95 pancreas transplants.

In addition to being the chairman of 6 national congresses, he has also been an invited speaker at 12 international and 65 national scientific congresses. Dr. Alper Demirbaş was married and the father of 1 girl and 1 boy.


Eczacibasi Medical Award of 2002, Akdeniz University Service Award of 2005, Izder Medical Man of the Year Award of 2006, BÖHAK Medical Man of the Year Award of 2007, Sabah Mediterranean Newspaper Scientist of the Year Award of 2007, ANTIKAD Scientist of the Year Award of 2009, Social Ethics Association Award of 2010, Işık University Medical Man of the Year Award of 2015, VTV Antalya's Brand Value Award of 2015.


Doctor of Medicine Degree Hacettepe University Faculty of Medicine Ankara, General Surgeon Ministry of Health Turkey EKFMG (0-477-343-8), University of Miami School of Medicine Member of Multiple Organ Transplant, ASTS Multiorgan Transplant Scholarship. Lecturer at Kyoto University. Lecturer at University of Essen, Research assistant at the University of Cambridge .

Professional Members:

American Society of Transplant Surgeons, American Transplantation Society Nominated, Middle East and Southern Africa Council Transplantation Society 2007, International Liver Transplantation Association, Turkish Transplantation Association, Turkish Society of Surgery, Turkish Hepatobiliary Surgery Association.


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Medically Reviewed by Professor Doctor Alper Demirbaş
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